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Fig. 4 | Acta Neuropathologica Communications

Fig. 4

From: Generation and characterization of new monoclonal antibodies targeting the PHF1 and AT8 epitopes on human tau

Fig. 4

Immunocytochemistry of representative tau pathology in human AD brain and JNPL3 Tg mice with new antibodies PHF17 and PHF20. Immuno-reactivity of previously characterized phospho-tau antibodies PHF1 and new tau antibodies PHF17 or PHF20 in the hippocampus of a control individual or a subject with AD, and in the spinal cord of 12 month old nTg and JNPL3 Tg mice. Arrows indicating NFTs in human brain or NFT-like inclusion pathology in JNPL3 mice. Asterisk depicting dystrophic neurites within senile plaques. Bar = 100 μm, and 200 μm for insets

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Acta Neuropathologica Communications

ISSN: 2051-5960

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